Kaabista Murqaha Ka-hortagga Estrogen Steroids Budada Cad Tamoxifen Citrate Nolvadex
Faahfaahin Degdeg ah
Alaabta: Nolvadex (Tamoxifen Citrate)
CAS No: 54965-24-1
MF: C26H29NO
MW: 371.51
daahirnimo: 99%
Barta karkarinta: 482.3°C at 760 mmHg
Kaydinta: Waxa lagu xidhay 2ºC -8ºC
Meesha dhalaalka: 140-144 °C
dhibic toos ah: 356.5ºC
Qaab dhismeedka:
Einecs No: 234-118-0
Heerka: Heerka Ganacsiga
Alaabada kale ee Ka-hortagga Kansarka: Tamoxifen Citrate, Clomiphene Citrate, Toremifene Citrate, Anastrozole, Raloxifene hydrochloride, Fulvestrant, Letrozole, Crotamiton
Isticmaalka:Tamoxifen waa hormoon dumar ah oo xannibi kara ficillada estrogen, badanaa waxaa loo isticmaalaa daaweynta noocyada kansarka naasaha ee ragga iyo dumarka.
Daaweynta Kansarka Steroids ee aanu bixino
| Tamoxifen Citrate | wakiilka non-steroid |
| Exemestane | daawada aromatase |
| Anastrozole | loo isticmaalo marka la isticmaalayo xaddi la taaban karo ee steroids aromatizing |
| Stanozolol | Wareegyada Goynta |
| Toremifene Citrate | Modulator receptor Estrogen-ka xulashada non-steroidal |
| Drostanolone Propionate | Isteeroodhka anabolic |
| Methenolone Enanthate | assimilation hormoonka borotiinka firfircoonida xooggan ee beerka |
| 17-methyltestosterone | androgen iyo Albumen steroids assimilation |
| Fluoxymesterone | waxaa loo isticmaali karaa sidii qalab dawo |
| Formestan | Waxa loo istcimaalaa sidii xayndaab enzyme caraf udgoon |
Cuntada Nolvadex
Budada: 1 garaam oo Tamoxifen Citrate ah
Waxay soo saartaa: fiirsashada ugu badan ee la sameeyay - 20 mg / ml
Shuruudaha:
1 garaam oo Tamoxifen Citrate ah
1 beaker ku habboon xajinta mugga dareeraha
19.6 ml oo ah Glycerol
29.4 ml oo ah 190 Cadayn Khamri Hadhuudh
Budada: 1 garaam oo Tamoxifen Citrate ah
Waxay soo saartaa: fiirsashada ugu badan ee la sameeyay - 20 mg / ml
Shuruudaha:
1 garaam oo Tamoxifen Citrate ah
1 beaker ku habboon xajinta mugga dareeraha
9.8 ml oo ah PEG 600
39.2 ml oo ah 190 Cadayn Khamri Hadhuudh
Isticmaalka Nolvadex iyo qiyaasta
| Kansarka Naasaha | 10 ilaa 20 mg afka laba jeer maalintii |
| Kansarka naasaha ee metastatic | 20 ilaa 40 mg oo loo qaybiyay |
| Haweenka qaba Kansarka Ductal Carcinoma | 20 mg maalintii muddo 5 sano ah |
| Yaree kansarka naasaha | 20mg maalin kasta muddo 5 sano ah |
| Kansarka naasaha ee qanjidhada togan, kala-baxa axillary | 10 mg oo afka ah 2 ilaa 3 jeer maalintii muddo 5 sano ah. |
| Gabdhaha da'doodu u dhaxayso 2 ilaa 10 sano oo qaba McCune-Albright Syndrome | 20 mg maalintii hal sano |
Codsiga Nolvadex
1: Tamoxifen Citrate Isticmaalka Kansarka
| Tamoxifen citrate | La ansixiyay si looga hortago: Kansarka naasaha ee haweenka khatarta sare ugu jira cudurka. |
| Kansarka naasaha ee dumarka iyo ragga | |
| lagu baranayo daawaynta noocyada kale ee kansarka. |
2: Faa'iidooyinka Tamoxifen
A. Tamoxifen waxay hoos u dhigtaa ama joojisaa korriinka unugyada kansarka ee horeba ugu jiray jidhka.Waxay ka caawisaa ka ilaalinta kansarka naasaha asalka ah inuu soo laabto waxayna ka caawisaa ka hortagga kansarka cusub ee naaska ka soo horjeeda.Waxa kale oo ay hoos u dhigtaa halista kansarka naasaha ee haweenka khatarta sare leh u leh cudurkan.
B. Tamoxifen waxa loo isticmaalaa ka hortagga iyo daawaynta kansarka naasaha kuwaas oo tijaabiyey in ay leeyihiin estrogen reseptors (ER+).Waxay xannibtaa saamaynta hormoonka Estrogen uu ku leeyahay unugyada kansarka waxayna hoos u dhigtaa fursadda uu kansarka naasuhu u korayo.Inta badan waxaa loo yaqaan "anti-estrogen".
C. Tamoxifen ayaa aad waxtar ugu leh hoos u dhigida khatarta soo noqoshada kansarka naasaha.Dumarka hore u lahaa kansarka naasaha, tamoxifen waxay sidoo kale hoos u dhigtaa halista kansarka naasaha ee naaska ka soo horjeeda (is khilaafsan)
D. Dumarka postmenopausal, daawaynta laba marxaladood ah oo la isticmaalayo tamoxifen ka dibna aromatase inhibitor, sida anastrozole (Arimidex), exemestane (Aromasin), ama letrozole (Femara) ayaa laga yaabaa inay u shaqeyso si ka fiican marka loo eego qaadashada tamoxifen.
